Marco Pessoa

Research Scientist (Embrapa).

Genomics, plant genetic resources, and breeding.

contact: marco [at] marcopessoa.com

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on the consistency of genome assemblies

from a blog post by C. Titus Brown

This is from a blog post by C. Titus Brown about the Assemblathon 2 paper. Since we are currently dealing with genome assemblies I though it would be nice to post this here for future reference.

We need to clearly state that each assembly is a computational hypothesis, developed from noisy data using approximate computation, and that this assembly must be treated with skepticism. And we need to stop treating the output of programs published in peer-reviewed articles as if they are tablets handed down from on high, correct until proven wrong – they worked once, for one group, but that hardly means they’re robust or even particularly correct.

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